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NPR | Why is there a supplement craze if they don’t even work?

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This message comes from MS Now. AI is moving fast. What's real? What's hype? And where is it all headed?

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On why is this happening, Chris Hayes talks with the leading experts to make sense of it. The AI endgame, a special series from MS Now. Listen wherever you get your podcasts.

Melanie Banish
Melanie Banish

This is planet money from NPR.

Jane Black
Jane Black

You may have noticed we are living in the midst of a supplement craze. People are Vitamaxing, biohacking so they can live longer. Everyone's talking about gut health.

Sarah Gonzalez
Sarah Gonzalez

I feel very aware of my gut health right now. It's true. The supplement industry is a $70,000,000,000 industry in The United States and growing fast. We are talking protein powders, pre workouts, probiotics, fat burners.

Jane Black
Jane Black

There's joint health, gut health. There's glowing skin. I love glowing Better

Sarah Gonzalez
Sarah Gonzalez

sleep, stronger nails, all of that.

Jane Black
Jane Black

Seventy five percent of Americans take supplements.

Sarah Gonzalez
Sarah Gonzalez

A lot of people.

Jane Black
Jane Black

Yeah. Like, a 100,000 different options you can choose from.

Sarah Gonzalez
Sarah Gonzalez

Now supplements are everything from creatine or bovine colostrum, sometimes put in a martini, to your daily vitamin c gummies or echinacea. And because there are so many supplements out there, we kinda wanted to see, like, how easy it is to get a new supplement pill or gummy on the market. Like, could we make a supplement? Okay. What if we wanna make a supplement?

Frank Cantone
Frank Cantone

Okay.

Sarah Gonzalez
Sarah Gonzalez

Like a real NPR Planet Money branded supplement. Awesome.

Jane Black
Jane Black

This is Frank Cantone, the chiseled CEO of SMP Nutris supplement manufacturing partner. They make supplements.

Frank Cantone
Frank Cantone

Capsules, tablets, powders, soft gels, gummies.

Jane Black
Jane Black

And then brands or influencers or podcasts sell them under their own labels.

Sarah Gonzalez
Sarah Gonzalez

I think it would be cool to have, like, a little microphone shaped gummy or a little planet or a little money gummy. A money gummy.

Frank Cantone
Frank Cantone

We could do those.

Sarah Gonzalez
Sarah Gonzalez

Or maybe we do a powder that you just, like, add water to and down it real quick.

Jane Black
Jane Black

And it's called the money shot.

Sarah Gonzalez
Sarah Gonzalez

The money shot is the perfect name.

Frank Cantone
Frank Cantone

First and foremost, I think what's important would be to define the market.

Sarah Gonzalez
Sarah Gonzalez

Frank really wanted us to think about our planet money audience and what supplement you find people might want. You know, smart, busy, capable people.

Frank Cantone
Frank Cantone

So do we want something that helps people focus? Right? Do we wanna help people have more energy? Is that the type of

Marion Nestle
Marion Nestle

product that we want to offer?

Sarah Gonzalez
Sarah Gonzalez

That sounds great. I'm always tired.

Jane Black
Jane Black

There are so many supplements already out there that claim to help with brain function or focus. There's ashwagandha or theanine.

Sarah Gonzalez
Sarah Gonzalez

But for our potential focus gummy or shot, Frank actually suggests creatine or lion's mane or other mushrooms if we want focus.

Jane Black
Jane Black

Focus would be awesome. Also, would like thicker hair.

Frank Cantone
Frank Cantone

Okay.

Jane Black
Jane Black

Can I do that?

Frank Cantone
Frank Cantone

Yeah. I mean, we could add collagen to this cocktail, which would help with hair growth and hair thickness.

Sarah Gonzalez
Sarah Gonzalez

Hold on. We're gonna have a gummy that's like, it gives you focus and it gives you thicker hair?

Frank Cantone
Frank Cantone

It's doable for sure.

Sarah Gonzalez
Sarah Gonzalez

Is it smart?

Frank Cantone
Frank Cantone

I feel like it it hits two needs that everyone really has a problem with. Right?

Jane Black
Jane Black

I love how Frank just wants to make things happen for us.

Sarah Gonzalez
Sarah Gonzalez

I know. If there is something that you want your mind or your body to do, Frank will find the ingredient for you. Like, you wanna burn fat? Maybe throw some green tea in there.

Jane Black
Jane Black

Frank says people associate it with weight loss.

Frank Cantone
Frank Cantone

It's typically found in weight management products so they can kind of put it in that boat if they want to, but the green tea is really there for some energy benefits.

Jane Black
Jane Black

We walked through all the things, ingredients, shapes, flavors.

Sarah Gonzalez
Sarah Gonzalez

Kiwi? For sure. Honeydew? Honeydew is a super No

Frank Cantone
Frank Cantone

no one does just kiwi. Oh. They do strawberry kiwi.

Sarah Gonzalez
Sarah Gonzalez

We docked colors. Ours would be green, of course. And right there on the spot, we got an estimate for the smallest possible order of our fully customized, I would argue, berry tasty supplement.

Frank Cantone
Frank Cantone

It's gonna be around 8,333 bottles. Based upon the ingredients we're talking about, it's gonna range from, like, $4.50 to $7.

Sarah Gonzalez
Sarah Gonzalez

$4 times 8,003 bottles?

Marion Nestle
Marion Nestle

Mhmm.

Sarah Gonzalez
Sarah Gonzalez

So 33,000, and then you do half upfront.

Jane Black
Jane Black

Which is not that bad if you're looking to start your own business, but there is a cheaper option too.

Frank Cantone
Frank Cantone

For our stock formulas, you're in the game for, you know, $5,500.

Sarah Gonzalez
Sarah Gonzalez

Yeah. They do have more than 800 gummies and pills and powders ready to go already. These are their stock options that we can just slap our own Planet Money label on and call it our special Planet Money energy supplement even though this exact same gummy, same color, same flavor, same shape, is being sold already by someone else under a different label.

Frank Cantone
Frank Cantone

Be happy to send you samples right after this call, you could try that energy gummy on the website.

Jane Black
Jane Black

Yep. They even had an energy gummy with green tea in it.

Sarah Gonzalez
Sarah Gonzalez

So could we say on the label, like, this will help with mental clarity and burn fat?

Frank Cantone
Frank Cantone

We'll guide you down the right way to say it. I'd say supports metabolism or, you know Collective.

Sarah Gonzalez
Sarah Gonzalez

Okay. Supports metabolism. Exactly. Hello, and welcome to Planet Money. I'm Sarah Gonzales.

Jane Black
Jane Black

And I'm Jane Black.

Sarah Gonzalez
Sarah Gonzalez

Jane is a food politics reporter in DC. She has been watching what people call big wellness get bigger and bigger and more and more powerful.

Jane Black
Jane Black

And if you think supplements are popular now, just wait. Sales are expected to double over the next seven years.

Sarah Gonzalez
Sarah Gonzalez

Now, we are not going to make our own supplement.

Jane Black
Jane Black

We are not gonna sell one.

Ira Glass
Ira Glass

We were gonna do it.

Jane Black
Jane Black

We were gonna do it.

Ira Glass
Ira Glass

We were gonna do it.

Jane Black
Jane Black

You know, started to make us a little bit nervous. Which is kind of a bummer because we do want more energy. And thicker hair.

Sarah Gonzalez
Sarah Gonzalez

And thicker hair, apparently.

Jane Black
Jane Black

It was so tempting, especially because it's just so easy to make one.

Sarah Gonzalez
Sarah Gonzalez

The supplement industry has been fully cashing in on our love of silver bullets and a magic pill.

Jane Black
Jane Black

Today on the show, how lax regulations are making that possible

Sarah Gonzalez
Sarah Gonzalez

and why Americans wouldn't have it any other way.

Jane Black
Jane Black

Yeah. Like, what do you take?

Frank Cantone
Frank Cantone

Definitely taking a multivitamin, taking magnesium before bed, berberine, typically before a heavy meal. I'm taking trace minerals, take some dien dolomethane, boron, k two and d three, and a fat soluble soft gel, fifteen grams of creatine before my second coffee.

Sarah Gonzalez
Sarah Gonzalez

Frank, this is so many supplements.

Frank Cantone
Frank Cantone

It it's not as many as you would think. It's like on a given day, six or seven.

Ira Glass
Ira Glass

This is Ira Glass. On This American Life, one that we like is a good mystery. Sometimes about really big things, but most times, the little mysteries are the best. Our lost and found is currently filled with pants. I don't know what I I I've never seen this happen.

Ira Glass
Ira Glass

Wait.

Sarah Gonzalez
Sarah Gonzalez

This is true?

Ira Glass
Ira Glass

This is true. Mysteries of every size each week, This American Life, wherever you get your podcasts.

Jane Black
Jane Black

Okay. We are not here to prove or disprove whether supplements work, but we do want to say that experts and scientists tend to agree there is no evidence that supplements make healthy people healthier.

Sarah Gonzalez
Sarah Gonzalez

Now if you're pregnant, there is evidence that folic acid decreases the risk of certain birth defects. And if you have a condition or you're deficient in something, like you're anemic or deficient in iron, then, yeah, sure. An iron supplement could help with that if a doctor recommends it. But if you're not deficient, then you probably don't need it. Frank Cantone, the supplement maker who takes not that many supplements every day, he is a big believer in supplements.

Sarah Gonzalez
Sarah Gonzalez

Frank came to the supplement business from the real estate and clothing and thoroughbred racehorse trainer business. And his social media is still pretty horse heavy.

Frank Cantone
Frank Cantone

I just get vitamins, ads, and horse ads. That's all I have.

Jane Black
Jane Black

Okay. But now, Frank knows a lot about supplements. He has built this huge supplement factory in Florida that he says makes millions of supplements a year, and he wants the industry to be reputable and safe. When people ask for something impossible, even us, he says no.

Sarah Gonzalez
Sarah Gonzalez

I would like to sleep better at night and have more energy during the day.

Frank Cantone
Frank Cantone

Yeah. So you're not gonna be able to make one product that puts you to sleep and then wakes you back up. We've had people try to do that. Really? You definitely got that request before.

Sarah Gonzalez
Sarah Gonzalez

Frank says he also gets requests all the time to like jam pack supplements with so much of one ingredient that it becomes unsafe. And he will say no to that too.

Frank Cantone
Frank Cantone

You do have your bad actors where someone comes to us. We wanna make this. And we say, well, that is not exactly possible. So they'll go to someone else and they'll say, hey, can you make this? Someone says, yes.

Frank Cantone
Frank Cantone

All of a sudden, it's in the market, but no one's checked what's really in it.

Jane Black
Jane Black

Frank says a lot of people selling supplements came to this business because supplements are a good business. Often, the people who come to the industry used to sell some other less profitable products.

Frank Cantone
Frank Cantone

Yoga mats or, you know, water bottles, anything that it might be, they wind up coming to supplements at some point because it's something people take every month and they reorder. Right? So it attracts entrepreneurs from different markets to say, hey, I can only sell this guy so many, you know Watermelon. Mats. Right?

Frank Cantone
Frank Cantone

Yeah. He's gonna use it once or twice. I can sell him the same green super fruit powder every month, and that customer lifetime value is gonna go way up.

Sarah Gonzalez
Sarah Gonzalez

It's hard to say exactly why supplements are so popular right now.

Jane Black
Jane Black

Frank told us that the supplement business really, really took off during COVID. In fact, supplement sales have increased around 50% since before the pandemic. There's also the wellness influencers on TikTok and Instagram. They've also contributed to the jump in sales.

Sarah Gonzalez
Sarah Gonzalez

And then there's also just, a lot of distrust in institutions and the government and the pharmaceutical industry right now. And even though supplement makers are companies too, people feel like they're this more natural anti establishment alternative.

Jane Black
Jane Black

Even our own health and human services secretary, RFK junior, he's a big fan of supplements. His acting FDA commissioner wants to make them even easier to make and to sell.

Sarah Gonzalez
Sarah Gonzalez

And there's a long history of people in The United States trying to test the limits of the free market and sell you some magic pill.

Jane Black
Jane Black

One of my favorite stories is in the nineteen tens. There was this really popular supplement. It was claiming it could cure malnutrition using strychnine, which is in rat poison.

Sarah Gonzalez
Sarah Gonzalez

Sounds lovely. In the nineteen twenties and thirties, people were tinkering with yeast, trying to supercharge it with vitamins, claiming it would solve a bunch of things, including something called furry tongue, which is what it sounds like.

Jane Black
Jane Black

And around that same time, a guy entranced for the power of radiation sold radioactive water as a cure for fatigue, which was popular until a New York tycoon's jaw fell off.

Sarah Gonzalez
Sarah Gonzalez

His jaw fell off.

Jane Black
Jane Black

Just disintegrated. It just Right. It just completely disappeared.

Sarah Gonzalez
Sarah Gonzalez

Fifties, doctors are calling all of this medical quackery. Wonder why.

Jane Black
Jane Black

But it was really hard to do anything about it.

Sarah Gonzalez
Sarah Gonzalez

Yeah. The growth of the industry isn't just about how badly Americans want a magic pill. It's also thanks to years of lax regulations.

Jane Black
Jane Black

Supplements have always been really hard to regulate. They're kind of a food because, you know, they're designed to supplement your diet. But they're also pills or gummies or powders. You know, they come in a jar with a label claiming to address your health problems. They feel like a drug.

Jane Black
Jane Black

But drugs have to go through this really rigorous testing to prove that they work. Supplements do not. Supplements live in this weird no man's land.

Sarah Gonzalez
Sarah Gonzalez

When the Food and Drug Administration was created in nineteen o six, there was no mention of supplements. But over the years, the FDA has tried to regulate them many times. Like in 1966, the FDA proposed a disclaimer, be displayed in prominent type, like right there on the supplement bottle, basically saying that you can get your vitamins and minerals from the foods we eat and that there is no scientific basis for routine use of supplements.

Jane Black
Jane Black

But people did not like that.

Marion Nestle
Marion Nestle

They did

Jane Black
Jane Black

not. And Congress got more than 2,000,000 letters, which was actually more than they ever got during Watergate. So no disclaimers.

Sarah Gonzalez
Sarah Gonzalez

Yeah. Didn't go through. In the seventies, the FDA's official position was still that supplements are, quote, nutritionally irrational.

Jane Black
Jane Black

And that's like a giant government exclamation point.

Sarah Gonzalez
Sarah Gonzalez

Yeah. But it didn't matter to anyone. Every time the FDA and Congress has tried to make supplement rules, the thing that got in the way was you, the consumer. Massive consumer backlash.

Jane Black
Jane Black

This is Melanie Banish.

Melanie Banish
Melanie Banish

The public really, really loves their supplements. Yeah.

Jane Black
Jane Black

Melanie is a lawyer who focuses on food and drug regulations at the Environmental Working Group, which has for years advocated for safer consumer products and more regulation. She says the last time Congress even attempted to regulate supplements was in the early nineties, and the consumer revolt that followed basically killed any serious effort to regulate supplements ever again.

Sarah Gonzalez
Sarah Gonzalez

That story starts in Kent, Washington. There was some alternative medicine clinic, and the proprietor there was accused of illegally injecting patients with these high dose concoctions of vitamins and minerals that the FDA repeatedly told them were unsafe.

Jane Black
Jane Black

One day, FDA agents show up with the local police and kick down the door of the clinic. It makes the front page of the New York Times, and the supplement industry sees this big newsy raid as an opportunity to fight back. They launch an incredibly effective counter offensive.

Sarah Gonzalez
Sarah Gonzalez

They got people to write thousands of letters to president George h w Bush, to congress, and the FDA saying, like, please, please, please, please, please, do not touch our supplements. They even got health food stores to join in on the revolt.

Melanie Banish
Melanie Banish

Health food stores put black curtains over the supplement aisle and the vitamin aisle and said, this is the future you're looking at if congress gets its way.

Jane Black
Jane Black

Some stores even refused to sell supplements on certain days to, you know, make people really live out the nightmare of this world without vitamins.

Melanie Banish
Melanie Banish

They got Mel Gibson to do an ad.

Sarah Gonzalez
Sarah Gonzalez

In the ad, you see a SWAT team kicking open the door of their SWAT band. They rush toward, I guess, Mel Gibson's mansion in full SWAT gear. They're scaling the side of the building. They get inside, night vision goggles through the living room, guns drawn, and then they spot Mel Gibson.

Ira Glass
Ira Glass

Freeze drug enforcement.

Melanie Banish
Melanie Banish

He's standing in his bathrobe, and the FBI swoops in and knocks the vitamins out of his hands.

Ira Glass
Ira Glass

Oh. Oh, god. Hey. It's only vitamins. It's only it's only vitamins.

Sarah Gonzalez
Sarah Gonzalez

On the screen, it says, protect your right to use vitamins. Call congress now.

Ira Glass
Ira Glass

Vitamin c, you know, like in oranges.

Sarah Gonzalez
Sarah Gonzalez

Congress gets an earful, and congress gets the message. Supplements are kinda untouchable in The US.

Jane Black
Jane Black

Technically, congress did pass a big supplement law in 1994. It's called the dietary supplement health and education act. But it is so lax that experts in this field don't even consider supplements to be regulated almost at all.

Sarah Gonzalez
Sarah Gonzalez

In fact, the law gave supplement makers more freedom, including something they'd always wanted: the legal right to claim on their labels that supplements were actually improving your health. And they could now claim this as long as they avoided a couple keywords.

Jane Black
Jane Black

Okay. So a supplement maker cannot say their pill diagnoses, prevents, cures, treats, or mitigates a disease like Alzheimer's, but they can say it helps improve your memory, which is a pretty subtle distinction.

Melanie Banish
Melanie Banish

You know, it's not always clear to me what the difference is between, say, helping to maintain your blood sugar levels versus using it as part of a healthy diet to help maintain healthy blood sugar levels.

Sarah Gonzalez
Sarah Gonzalez

Wait. Is one of those okay and the other one is not okay?

Brittany Luse
Brittany Luse

Yeah.

Sarah Gonzalez
Sarah Gonzalez

They sound exactly the same.

Melanie Banish
Melanie Banish

Yeah. So I have trouble distinguishing.

Sarah Gonzalez
Sarah Gonzalez

This is the thing that the supplement maker, Frank, was kind of, like, guiding us on. Right? He's like, you can't say it burns fat. You gotta say it supports metabolism. So here's a little news you can use.

Sarah Gonzalez
Sarah Gonzalez

Melanie says, if the front of your supplement bottle says supports x or promotes y, that should be a signal to you that it is not actually proven to do anything. If you turn over your supplement bottle right now, you will even see in tiny fine print that the claims on the bottle have, quote, not been evaluated by the FDA.

Jane Black
Jane Black

And sure, the supplement makers are supposed to have something to back up their claims, and there are a bunch of studies out there that say these things work. But you have to look at how good those studies are and who's funding them. There's a lot of conflict of interest there. There is nothing in the regulation that requires supplement makers to prove their product does what it says it does.

Sarah Gonzalez
Sarah Gonzalez

So what's the point? What's the point of a supplement if it's not supposed to actually work on the thing it's claiming to work on?

Melanie Banish
Melanie Banish

Hoops and dreams.

Sarah Gonzalez
Sarah Gonzalez

The law also says you don't even have to prove your supplement is safe before you sell it to people. Unless there's one unless unless it is a brand new, never before used ingredient in a supplement. Then you do need to show some some paperwork.

Jane Black
Jane Black

Yeah. We have finally stumbled on an actual rule here. I'm excited. If your supplement includes a totally brand new ingredient, that is one of the few times the company has to notify the FDA and show them their safety studies. Now they don't have to prove that it's safe.

Jane Black
Jane Black

This is supplement regulation, so that would be a wicked high standard. The law just requires that a supplement will, quote, reasonably be expected to be safe.

Sarah Gonzalez
Sarah Gonzalez

And if that doesn't make you feel super safe, then you should know that there is also a workaround to this rule. And there's one supplement more than any other supplement, according to Melanie, that really exemplifies this fun workaround. How companies can get their supplements onto store shelves without proving that they're even reasonably expected to be safe. It involves glowing jellyfish.

Jane Black
Jane Black

It all started with a young man from Wisconsin.

Melanie Banish
Melanie Banish

Who, I think, had this epiphany and really honed in on jellyfish.

Sarah Gonzalez
Sarah Gonzalez

Every good supplement starts with an epiphany. This was in the nineties. The young man was named Mark Underwood, and he had an idea for a new supplement that would improve memory. And the story goes that the idea came from this moment with his mom who had MS, multiple sclerosis.

Jane Black
Jane Black

And the details come from this really great article in Wired. We pulled it up in the studio with Melanie, and apparently, this guy's mom was always looking out for things that could help her. Since the disease had limited her body, Diane, the mother, says that she was attracted to the way jellyfish seemed to move so easily and that's what led her to wonder if the marine animal might hold the key to a medical breakthrough.

Sarah Gonzalez
Sarah Gonzalez

Diane, the mom, apparently tells her son about this.

Jane Black
Jane Black

And he took to it like a dog with a bone.

Sarah Gonzalez
Sarah Gonzalez

Hold on. Hold on. Hold on.

Marion Nestle
Marion Nestle

Mhmm.

Melanie Banish
Melanie Banish

So it it wasn't even about memory? Why did we think that jellyfish have good memory?

Sarah Gonzalez
Sarah Gonzalez

Don't they like famously not have brains?

Jane Black
Jane Black

Yeah. Exactly. They don't have brains. But despite jellyfish not having brains.

Sarah Gonzalez
Sarah Gonzalez

Or hearts.

Jane Black
Jane Black

Or hearts. Mark Yep. Wants to make his memory boosting jellyfish supplement anyway.

Sarah Gonzalez
Sarah Gonzalez

Yeah. And he's not gonna use jellyfish from, like, the ocean for this. Okay? He wants to use something that mimics the protein found in glowing jellyfish.

Jane Black
Jane Black

Because they have to be glowing.

Sarah Gonzalez
Sarah Gonzalez

So this is a synthetic made in a lab version of the protein that causes jellyfish to glow. Okay? And he sets out to now sell that product. And on his marketing material, he promises his supplement will, quote, not cause any glowing. Wow.

Sarah Gonzalez
Sarah Gonzalez

So it will not make you glow, but it will apparently improve your memory.

Jane Black
Jane Black

So what does it take for him to get that into stores or sell it online?

Sarah Gonzalez
Sarah Gonzalez

Well, the jellyfish company first went to the FDA, but the FDA was like, yeah. No. It doesn't meet our safety threshold, which is honestly a pretty low threshold.

Jane Black
Jane Black

And when the company ran it by the FDA again a few years later, FDA says, nope. We still don't think it's safe enough.

Sarah Gonzalez
Sarah Gonzalez

But there is a way around that pesky little FDA objection. There is a law from the food regulation world that supplement makers can take advantage of.

Marion Nestle
Marion Nestle

Uh-huh.

Sarah Gonzalez
Sarah Gonzalez

If you've heard our recent story on how untested chemicals sneak into our food, this might sound familiar. But if you are a food maker and you've just invented a new chemical or a new ingredient that has never been used in food before, you can just declare that your own brand new ingredient is safe, that it's generally recognized as safe or GRAS, g r a

Jane Black
Jane Black

s. So if you're having trouble getting your new supplement ingredient, like glowy jellyfish stuff, pass the FDA's review process, Melanie says you can just put it in a food product first.

Melanie Banish
Melanie Banish

So put it in a protein shake or something else, and then now it's part of the food supply.

Sarah Gonzalez
Sarah Gonzalez

Hold on. Melanie pointed to a supplement trade article that says industry lawyers even advise their clients to do this. Like, you can skip that pesky FDA hurdle. Just put your new ingredient in a food product first. And now you can add it to your brand new supplement as a generally recognized as safe product.

Sarah Gonzalez
Sarah Gonzalez

Ta da. And that is exactly what the glowy jellyfish guy did.

Melanie Banish
Melanie Banish

They said, We'll put it in food. And that was the birth of the shake.

Jane Black
Jane Black

The Prevagen shake. They called it NeuroShake. And the jellyfish company did formally notify the FDA they were now introducing the jellyfish thing as a food ingredient. The FDA again questioned the safety of the ingredient in the shake. But once you're talking about food ingredients, companies can actually ignore the FDA's concerns as long as they self certify that their ingredient is safe.

Sarah Gonzalez
Sarah Gonzalez

Yeah. That safety self certification allows them to bypass the FDA's review process. So the jellyfish company self certified that their synthetic lab made jellyfish stuff was safe to drink in a shake. Totally legal because we're talking about food products now.

Jane Black
Jane Black

And once they got into food, that gave them the right to add it to the supplement. That is the get around.

Sarah Gonzalez
Sarah Gonzalez

That is how we have this synthetic jellyfish shake and the synthetic jellyfish pill. And, actually, the pill was on the market the whole time. No one stopped them. Through all the back and forth with the FDA expressing concerns and all of that, they were just selling it anyway.

Jane Black
Jane Black

Between 2007 and 2015, the jellyfish company racked up more than a $165,000,000 in sales. Meanwhile, people were reporting side effects to the company that they were having chest pain and seizures and strokes while taking this supplement. But unless the FDA is aware of an imminent hazard or they do their own testing and can prove that a supplement is unsafe, which takes years and lots of money, the FDA can't take a product off the market. But the Federal Trade Commission can bring a case against them for false advertising.

Sarah Gonzalez
Sarah Gonzalez

And the FTC did that with the jellyfish supplement. They sued in 2017. And just a short, almost eight years later, the Blanketamine. Won its case. The company was claiming that their product was clinically proven to improve memory.

Sarah Gonzalez
Sarah Gonzalez

And the FTC said, there's one clinical trial, and it did not show their supplement improved memory. So now the label just says Prevagen for your brain. Nice. Vague promise there.

Jane Black
Jane Black

But people are still buying it. It's currently in the top five of Amazon's list of blended vitamin and mineral supplements.

Sarah Gonzalez
Sarah Gonzalez

And lesson, maybe synthetic lab made glowy fish stuff is one thing. Right? Like, maybe that feels totally different from, say, fish oil or collagen or herbal supplements like turmeric pills. But Melanie says even the ones that seem all natural or super familiar may not be what you think.

Jane Black
Jane Black

Take green tea supplements. That sounds like a thing that just grows in nature, but the green tea in your supplement is rarely the actual leaves that you see in your tea bag.

Sarah Gonzalez
Sarah Gonzalez

It's an extract made by bathing the tea leaves in a solvent, usually ethanol, to extract a particular antioxidant called EGCG, which is all the rage among influencers. But high concentrations of lab processed green tea EGCG extract is linked to acute liver damage and sometimes death.

Jane Black
Jane Black

Or turmeric supplements. They often contain 10 times the amount recommended by the World Health Organization. After the break, we're talking about the regular, everyday, familiar herbal supplements and vitamins that so many of us have in our kitchens right now.

Sarah Gonzalez
Sarah Gonzalez

Yeah. You're probably not gonna wanna hear this next part.

Speaker 8

On June 11, the globe's biggest sporting event comes to North America, the FIFA World Cup. The Super Bowl, you might say, averages something over a 100,000,000 live viewers, but the World Cup final, think, like, five times that much. The favorites, the under dogs, and the Americanization of the world's game. Listen now to the Sunday story from the Up First podcast on the NPR app. So I have

Sarah Gonzalez
Sarah Gonzalez

these like gummies, vitamin c, adult gummies c is what

Marion Nestle
Marion Nestle

they're called. Are you taking that?

Sarah Gonzalez
Sarah Gonzalez

It's like a little treat, you know. It's like a it's like a gummy bear, except maybe there's some vitamin c in there.

Marion Nestle
Marion Nestle

And you feel like you're making yourself healthy. Is Marion Nestle. If you're vitamin c deficient, it could be quite useful. I don't know anybody who's vitamin c deficient if they eat any fruits and vegetables at all. I mean, scurvy is not a major problem in The United States.

Marion Nestle
Marion Nestle

It's not a public health problem.

Sarah Gonzalez
Sarah Gonzalez

Yeah.

Jane Black
Jane Black

Marion is basically a legend in the food, nutrition, supplement world. She has a background in molecular biology, has written 17 books on the politics of food and supplements, and has been a public health advocate for decades.

Marion Nestle
Marion Nestle

I'm 89.

Sarah Gonzalez
Sarah Gonzalez

89. Good nutrition. Good nutrition? Is that what you so there's nothing really bad you buy?

Marion Nestle
Marion Nestle

I buy tortilla chips. I buy ice cream. I buy all kinds of things. I eat my share of junk food.

Sarah Gonzalez
Sarah Gonzalez

But vitamins? Supplements?

Jane Black
Jane Black

Do you take any?

Sarah Gonzalez
Sarah Gonzalez

No. No vitamin d? Vitamin d is not

Marion Nestle
Marion Nestle

a vitamin. It's a hormone that you get from exposure to the sun.

Sarah Gonzalez
Sarah Gonzalez

Sick burn, Marion. Sorry. So, yeah, no vitamin supplements for this true legend.

Marion Nestle
Marion Nestle

I wouldn't take it because I don't know what's in those packages. What it says on the label is not what's in the package.

Jane Black
Jane Black

For Marion, it's not just that supplements are unregulated when it comes to the safety of their ingredients. She's worried about an even more basic problem. Like, what even are the ingredients?

Marion Nestle
Marion Nestle

Your turmeric supplement may or may not have turmeric in it.

Sarah Gonzalez
Sarah Gonzalez

What? Don't you check the ingredient list and say does it say turmeric as an ingredient? Doesn't matter.

Marion Nestle
Marion Nestle

It doesn't have to have in it what it says on it.

Jane Black
Jane Black

Technically, supplements are supposed to contain what they say they do. But

Marion Nestle
Marion Nestle

Nobody has the resources to check and see whether those supplements have in them what it says on the label unless somebody sues the company. If if if there's no lawsuit involved, there's nobody minding the store.

Speaker 8

Is that is it the same

Sarah Gonzalez
Sarah Gonzalez

way with food? Like, if you read an ingredient in a food product as No.

Marion Nestle
Marion Nestle

No. No. No. No. That will be accurate.

Jane Black
Jane Black

Yeah. Because the FDA will sometimes spot check food ingredients to make sure they're for real.

Sarah Gonzalez
Sarah Gonzalez

But on a supplement

Marion Nestle
Marion Nestle

You have no way of knowing.

Jane Black
Jane Black

And and sometimes supplements have stuff in there that really shouldn't be in there.

Marion Nestle
Marion Nestle

Lead, arsenic, or other heavy metals.

Sarah Gonzalez
Sarah Gonzalez

There is a private supplement testing lab called ConsumerLab that Marion points to a lot. Id's whole business is testing supplements to see what is actually in them. And recently, they tested a bunch of turmeric pills on the market and found that one had no turmeric, basically, and others had more than even advertised.

Jane Black
Jane Black

And they have found similar variations in echinacea supplements and elderberry supplements. Consumer Labs found that more than two thirds of elderberry supplements sold on Amazon did not contain authentic elderberry at all.

Marion Nestle
Marion Nestle

This is true of every supplement.

Sarah Gonzalez
Sarah Gonzalez

Well, maybe not every, but

Marion Nestle
Marion Nestle

I can't think of a single supplement that ConsumerLab has investigated where it hasn't found wide variation.

Jane Black
Jane Black

According to a 2017 study, twenty percent of liver toxicity cases were tied to herbal and dietary supplements.

Sarah Gonzalez
Sarah Gonzalez

Over most of the last thirty years, supplement related liver failure increased eightfold, So much so that people started having to be put on wait lists for liver transplants. Now that might be because of user error, like people taking a bunch of these supplements in a day thinking more must be better, but maybe it's other reasons. It's really hard to pinpoint.

Jane Black
Jane Black

Marion says there are some supplements on the shelves that are maybe more trustworthy than others. If they're marked with an NSF or USP, that indicates that they've been third party tested, that the supplements do contain the ingredients listed, and that the amounts are accurate and not at harmful levels. Remember Frank, our supplement maker? His supplements are NSF certified.

Sarah Gonzalez
Sarah Gonzalez

And Marion thinks it is pretty important to point out that most supplements, whether they are certified or not, likely are not causing any real harm, even if they likely aren't causing any benefit.

Marion Nestle
Marion Nestle

Some of them are harmful, and that's a problem. But most of them are not particularly harmful. So there's a little risk, but it's not a big risk.

Jane Black
Jane Black

I mean, to be honest, that kind of surprised me. I mean, Marian Nessel, woman of science, you would think would be rabidly anti supplement. Honestly, she's kinda like, do whatever you want, people.

Marion Nestle
Marion Nestle

You know, this is like religion. You don't argue with people about religion. There's no evidence that they make healthy people healthier. But if people believe that these things are doing them good, I'm not going to argue with that. There's nothing I can say to dissuade them.

Marion Nestle
Marion Nestle

And I'm not even going to try.

Jane Black
Jane Black

Marion wrote the history on this. She knows that even when people see the science, it rarely makes them throw out their supplements.

Sarah Gonzalez
Sarah Gonzalez

I must admit, I have not thrown out my vitamin c gummies or my turmeric pills. Though, I don't know, Jane, maybe maybe I just won't buy them again.

Jane Black
Jane Black

Yeah. We were surprised that some of the experts we talked to, experts who advocate for supplement regulation and are well aware of all of these problems, they still take some supplements too. Maybe

Sarah Gonzalez
Sarah Gonzalez

it's totally irrational of us, but maybe it's not. Because there is one good thing that supplements do sometimes do for us, says Marion.

Marion Nestle
Marion Nestle

Supplements make people feel better. There's absolutely no question about that.

Sarah Gonzalez
Sarah Gonzalez

Did she just say supplements make people feel better?

Jane Black
Jane Black

Yeah. But it's not necessarily because their ingredients actually do what they say they'll do.

Sarah Gonzalez
Sarah Gonzalez

Yeah. It's this other thing.

Marion Nestle
Marion Nestle

It has a fabulous placebo effect.

Sarah Gonzalez
Sarah Gonzalez

Yeah. You feel like your vitamin c gummy helps you not catch a cold, and then you don't catch a cold. Placebos, baby.

Jane Black
Jane Black

Magic.

Marion Nestle
Marion Nestle

There's plenty of evidence that supplements are fabulous placebos. And in fact, I can tell you a story about a study that proved that. But it doesn't matter. Life is really hard these days. And if all it takes is a supplement pill to make people feel better, I'm, you know, I'm not gonna argue too much about it.

Sarah Gonzalez
Sarah Gonzalez

I love placebos.

Marion Nestle
Marion Nestle

Yeah. I do too.

Sarah Gonzalez
Sarah Gonzalez

They're so powerful.

Marion Nestle
Marion Nestle

I do too. I do too. So if you're gonna buy supplements, you buy from the most reputable company you can find, and keep your fingers crossed.

Sarah Gonzalez
Sarah Gonzalez

Just just cross your fingers, Jane.

Jane Black
Jane Black

Thank you so much, Mary Anne. I'm feeling feeling good about this. I'm feeling

Marion Nestle
Marion Nestle

really good.

Sarah Gonzalez
Sarah Gonzalez

You know what gets me about all this, Jane? If supplement makers were to just be, like, fully transparent. Right? They put on the bottle, there might not be that much turmeric in here, and it may cause liver damage, and it may not even be anti inflammatory like we're suggesting. I don't even think that would stop people from buying them.

Jane Black
Jane Black

Yeah. Probably not. I mean, we've got a hundred years of history that says nothing is gonna come between Americans and their supplements.

Sarah Gonzalez
Sarah Gonzalez

But you don't even take supplements, Jamie.

Jane Black
Jane Black

Right. I know. I mean, nothing's gonna come between you and your supplement.

Sarah Gonzalez
Sarah Gonzalez

Yeah. Yeah. Right. This episode was produced by Sam Yellow Horse Kessler, takes fish oil, edited by Mary Anne McCune, daily multivitamin, and fact checked by Sierra Juarez with help from Vito Emmanuel who do not take any supplements because, of course, our fact checkers don't. It was engineered by Robert Rodriguez with help from Jimmy Keeley, and Alex Goldmark is our executive producer.

Jane Black
Jane Black

Special thanks to Jensen Joes at the Center for Science in the Public Interest and Kiara Eisner, who wrote that great Wired article and now works for

Sarah Gonzalez
Sarah Gonzalez

NPR. I'm Sarah Gonzalez.

Jane Black
Jane Black

And I'm Jane Black. This is NPR. Thanks for listening.

Brittany Luse
Brittany Luse

Every episode of It's Been a Minute, NPR's What's happening in culture podcast starts by asking three questions. Who? How? Why now? If the culture's asking it, we're talking about it.

Brittany Luse
Brittany Luse

At NPR, we stand for your right to be curious and indulge your cultural curiosity. Follow It's Been A Minute wherever you get your podcasts, and we'll break down the zeitgeisty topics that are filling your feed.

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